In this evening's two Copa del Rey round of 16 first leg ties Cádiz were beaten by Celta 0-3, while Las Palmas won against Eibar at Ipurua, 2-3.
Segunda B side Cádiz had qualified after their opponents in the previous round, Real Madrid, had been disqualified for fielding an ineligible player, Cheryshev. The third tier side took Celta by surprise in the first 25 minutes, dominating play and creating almost all of the few chances on offer. However after Guidetti opened the scoring for Celta the home side weakened and were noticeably flagging for much of the second half as the visitors made the gulf between the sides count.
At Ipurua home side Eibar went ahead twice, through Hajrovíc and Saúl but were pegged back on each occasion by Las Palmas (Aythami, Wakaso). Eibar then lost two men (Hajrovíc and Escalante) to red cards in the last 10 minutes and Las Palmas made their numerical superiority count, stealing victory right at the death with Momo lashing a screamer right into the top corner in time added on.
In yesterday's matches Alvaro Negredo scored a hat-trick as Gary Neville enjoyed his second win in seven games in charge of Valencia with a 4-0 thrashing of Granada in the Copa del Rey.
Neville is still waiting for his first win in La Liga, but it would take a monumental collapse in next week's second leg for his side not to book their place in the Cup quarter-finals.
Cup specialists Athletic Club produced a stirring second-half comeback from 2-0 down to take a 3-2 lead into the second leg of their last-16 tie against Villarreal.
The visitors counter-attacked to perfection before the break to take a commanding lead through Leo Baptistao and Samu Garcia despite resting a host of first-team regulars to prioritise their push for a top-four finish in La Liga.
However, Inaki Williams's early strike after half-time brought last year's finalists back into the game before Aritz Aduriz came off the bench to score his 22nd goal of the season and Aymeric Laporte rounded off the comeback 10 minutes from time.
2010 winners Sevilla dominated their all-Seville affair against city rivals Betis at the Villamarín where they have not lost since 2006. Krohn-Dehli set Unai Emery's side on their way with a 14th minute opener and Krychowiak stabbed in a second at the back post after some poor defending from the home side. Betis had the chance to redeem themselves and mask the scoreline when a penalty was awarded late on, although replays showed that Dani Ceballos had flung himself instants before Kolo came in with the challenge. It made no difference, as Rubén Castro his spot-kick wide and over as it ended 0-2 to Emery's men.
Mirandes, the only other side apart from Cádiz from outside the top flight left in the competition, maintained their hopes of reaching the last eight. The second division side went ahead through Alex Ortiz after 24 minutes, but Alberto Lopo's late equaliser rescued a 1-1 draw for Deportivo la Coruna.
Holders Barcelona got revenge over local rivals Espanyol after being held 0-0 on Saturday in the first of three Catalan derbies in 10 days. Luis Enrique's side thrashed the visitors 4-1 in a bad-tempered affair that finished with a confrontation in the tunnel between the sides that had to be broken up by security guards and the coaching staff from both teams.
La Liga leaders Atletico Madrid also faced a derby, theirs against Rayo Vallecano, and the honours were shared on the night at Vallecas. Nacho opened the scoring for the home side, but Saul got Simeone's side a precious away goal after 66 minutes.